Testo-Cypmax Maxtreme, for intramuscular injection, contains Testosterone Cypionate that is the oil-soluble 17 (beta)- cyclopentylpropionate ester of the androgenic hormone testosterone.
Testosterone Cypionate is a white or creamy white crystalline powder, odorless or almost so and strong in air. It is insoluble in water, freely soluble in alcohol, chloroform, dioxane, ether, and soluble in vegetable oils.
Testo-Cypmax Maxtreme – Clinical Pharmacology
Endogenous androgens are accountable for normal growth and improvement of the male intercourse organs and for upkeep of secondary sex characteristics. These effects include boom and maturation of the prostate, seminal vesicles, penis, and scrotum; development of male hair distribution, which includes beard, pubic, chest, and axillary hair; laryngeal enlargement, vocal twine thickening, and changes in body musculature and fats distribution. Drugs on this elegance also cause retention of nitrogen, sodium, potassium, and phosphorous, and decreased urinary excretion of calcium. Androgens were stated to boom protein anabolism and decrease protein catabolism. Nitrogen balance is improved simplest when there is enough consumption of energy and protein.
Androgens are answerable for the increase spurt of early life and for eventual termination of linear growth, brought approximately by way of fusion of the epiphyseal growth centers.
In children, exogenous androgens boost up linear growth rates, however may reason disproportionate development in bone maturation. Use over long intervals may result in fusion of the epiphyseal increase facilities and termination of the increase process. Androgens were said to stimulate production of purple blood cells by way of improving production of erythropoietic stimulation factor.
During exogenous management of androgens, endogenous testosterone release is inhibited via remarks inhibition of pituitary luteinizing hormone (LH). At huge doses of exogenous androgens, spermatogenesis can also be suppressed through remarks inhibition of pituitary follicle stimulating hormone (FSH).
There is an absence of giant proof that androgens are effective in fractures, surgery, convalescence, and functional uterine bleeding.
Testosterone esters are less polar than loose testosterone. Testosterone esters in oil injected intramuscularly are absorbed slowly from the lipid phase; thus, Testosterone Cypionate can be given at periods of to 4 weeks.
Testosterone in plasma is 98 percent certain to a selected testosterone-estradiol binding globulin, and about 2 percentage is loose. Generally, the amount of this sex-hormone binding globulin within the plasma will determine the distribution of testosterone between unfastened and bound forms, and the unfastened testosterone awareness will decide its half-lifestyles.
About 90 percentage of a dose of testosterone is excreted inside the urine as glucuronic and sulfuric acid conjugates of testosterone and its metabolites; about 6 percentage of a dose is excreted inside the feces, mostly within the unconjugated form. Inactivation of testosterone happens primarily inside the liver. Testo-Cypmax Maxtreme is metabolized to numerous 17-keto steroids via two unique pathways.
The half-lifestyles of Testosterone Cypionate when injected intramuscularly is approximately 8 days.
In many tissues the activity of testosterone seems to rely on discount to dihydrotestosterone, which binds to cytosol receptor proteins. The steroid-receptor complicated is transported to the nucleus in which it initiates transcription activities and cellular modifications related to androgen action.